Jonathan P Coles Selected Research

Craniocerebral Trauma (Head Injury)

3/2022	Survey evaluating clinical equipoise around platelet transfusion after head injury and traumatic intracranial haemorrhage (ICH) in patients on antiplatelet medications.
12/2021	Metabolic derangements are associated with impaired glucose delivery following traumatic brain injury.
11/2012	Imaging in the diagnosis and prognosis of traumatic brain injury.
7/2011	Validation of reference tissue modelling for [11C]flumazenil positron emission tomography following head injury.
1/2009	A combined microdialysis and FDG-PET study of glucose metabolism in head injury.
1/2008	Early derangements in oxygen and glucose metabolism following head injury: the ischemic penumbra and pathophysiological heterogeneity.
1/2006	Intersubject variability and reproducibility of 15O PET studies.
11/2004	Does induced hypertension reduce cerebral ischaemia within the traumatized human brain?
6/2004	Diffusion limited oxygen delivery following head injury.
5/2004	Effect of cerebral perfusion pressure augmentation with dopamine and norepinephrine on global and focal brain oxygenation after traumatic brain injury.

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Jonathan P Coles Research Topics

Disease

15	Craniocerebral Trauma (Head Injury) 03/2022 - 06/2002
11	Traumatic Brain Injuries (Traumatic Brain Injury) 12/2021 - 04/2004
7	Down Syndrome (Down's Syndrome) 01/2022 - 01/2016
7	Cognitive Dysfunction 01/2021 - 03/2011
6	Ischemia 01/2020 - 02/2004
5	Atrophy 01/2022 - 01/2017
5	Tauopathies 10/2020 - 12/2016
5	Frontotemporal Dementia (Semantic Dementia) 01/2020 - 01/2017
4	Alzheimer Disease (Alzheimer's Disease) 01/2021 - 01/2017
3	Dementia (Dementias) 01/2022 - 01/2017
3	Neuroinflammatory Diseases 01/2020 - 01/2017
3	Brain Injuries (Brain Injury) 03/2016 - 12/2002
2	Cerebral Cortical Thinning 01/2022 - 01/2017
2	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 10/2020 - 01/2017
2	Wounds and Injuries (Trauma) 11/2018 - 09/2016
2	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 10/2018 - 12/2016
2	Contusions 06/2013 - 11/2003
2	Hyperventilation 02/2007 - 06/2002
1	Delirium 01/2021
1	Brain Diseases (Brain Disorder) 01/2021
1	Disease Progression 01/2021
1	Stroke (Strokes) 10/2020
1	Corticobasal Degeneration 10/2020
1	Intracranial Hypertension 01/2020
1	Asymptomatic Diseases 01/2019
1	Primary Progressive Aphasia 10/2018
1	Brain Concussion (Cerebral Concussion) 01/2017
1	Inflammation (Inflammations) 01/2017
1	Lewy Body Disease (Lewy Body Dementia) 01/2017
1	Encephalitis (Encephalitis, Rasmussen) 01/2017
1	Coma (Comas) 09/2016
1	Amyloid angiopathy 01/2014
1	Edema (Dropsy) 06/2013
1	Hyperoxia 01/2008
1	Brain Ischemia (Cerebral Ischemia) 02/2007
1	Closed Head Injuries 02/2007
1	Hypocapnia 06/2004
1	Hyperemia 02/2004
1	Carotid Artery Diseases 12/2002

Drug/Important Bio-Agent (IBA)

12	Oxygen (Dioxygen)IBA 01/2020 - 06/2002
11	Amyloid (Amyloid Fibrils)IBA 01/2022 - 01/2014
8	Biomarkers (Surrogate Marker)IBA 10/2020 - 03/2016
5	Glucose (Dextrose)FDA LinkGeneric 12/2021 - 06/2002
4	2- (4'- (methylamino)phenyl)- 6- hydroxybenzothiazole (Pittsburgh compound B)IBA 01/2022 - 01/2014
3	Oxygen-15IBA 12/2021 - 01/2006
3	LigandsIBA 10/2018 - 01/2017
3	Glial Fibrillary Acidic ProteinIBA 01/2017 - 03/2016
3	Ubiquitin CIBA 01/2017 - 03/2016
3	6-chloro-2-(1-piperazinyl)pyrazine (CPP)IBA 11/2004 - 11/2003
2	Carbon DioxideIBA 01/2020 - 06/2002
2	Proteins (Proteins, Gene)FDA Link 01/2020 - 01/2019
2	Amyloid beta-PeptidesIBA 12/2019 - 01/2019
2	Pyruvic Acid (Pyruvate)IBA 01/2009 - 01/2008
2	Lactic Acid (Lactate)FDA LinkGeneric 01/2009 - 01/2008
2	Dopamine (Intropin)FDA LinkGeneric 05/2004 - 04/2004
2	Norepinephrine (Noradrenaline)FDA LinkGeneric 05/2004 - 04/2004
1	boldenone undecylenate (Equipoise)IBA 03/2022
1	splenotritin (TP3)IBA 01/2022
1	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 12/2021
1	PK 11195 (PK11195)IBA 01/2020
1	DNA-Binding Proteins (DNA Binding Protein)IBA 10/2018
1	neuromelaninIBA 10/2018
1	Monoamine Oxidase (MAO)IBA 10/2018
1	bupirimate (Nimrod)IBA 01/2017
1	(R)- (11C)1- (2- chlorophenyl)- N- methyl- N- (1- methylpropyl)- 3- isoquinolinecarboxamideIBA 01/2017
1	fluoromisonidazoleIBA 01/2016
1	TritiumIBA 01/2014
1	CarbonIBA 01/2014
1	Hemostatics (Antihemorrhagics)IBA 06/2013
1	Flumazenil (Romazicon)FDA LinkGeneric 07/2011
1	Neurotransmitter Agents (Neurotransmitter)IBA 03/2011
1	XenonIBA 10/2006
1	Propofol (Diprivan)FDA LinkGeneric 08/2003
1	Glutamic Acid (Glutamate)FDA Link 06/2002

Therapy/Procedure

5	Therapeutics 12/2016 - 04/2004
3	Critical Care (Surgical Intensive Care) 12/2021 - 10/2020
1	Platelet Transfusion (Blood Platelet Transfusions) 03/2022
1	Catheters 01/2009